What it can and cannot do
Detailed targeting lets you stack interests and behaviors to describe an audience. The limit is that much of it is inferred or self-declared, so it approximates intent rather than proving it. With Advantage+ audience and detailed targeting expansion, Meta may also deliver beyond your selections when it expects better results.
How to use it well
Treat detailed targeting as a seed, not a fence. It is a fine way to bootstrap a cold audience, but the durable signal comes from your pixel and a lookalike of real converters. Over-narrow stacking also shrinks the audience below what the algorithm needs to learn, which can trigger overlap and learning problems.